Professor Andres Floto
Andres Floto is a Professor of Respiratory Biology at the University of Cambridge, a Wellcome Trust Senior Investigator, and Director of the UK Cystic Fibrosis Innovation Hub.
His basic research is focused on combining machine learning with forward and reverse genetics to understand bacterial pathogenesis and host susceptibility to infection, and tackling the barriers to structure-guided antibiotic discovery using AI.
His clinical research is centred on experimental medicine studies of novel therapies and using machine learning to predict clinical deterioration in adults with cystic fibrosis and to forecast their disease trajectories.
Prof. Floto’s research is focused on understanding how immune cells interact with bacteria, how intracellular killing and inflammation are regulated and sometimes subverted during infection, how population-level whole genome sequencing can be used to reveal biology of bacterial infection, and how therapeutic enhancement of cell-autonomous immunity may provide novel strategies to treat multi drug resistant pathogens.
UK Cystic Fibrosis Innovation Hub
The Innovation Hub programme is designated as a series of strategic partnerships between the Cystic Fibrosis Trust and academic institutions, with shared goals, shared investment and shared governance. The aim is to provide a platform for exploring experimental medicine, to create a step-change in research to solve key issues in cystic fibrosis (CF).